功能性近红外光谱在抑郁症诊断及治疗监测中的临床应用

李夏颖, 洪素, 况利

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中国高校科技期刊信息汇聚平台
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重庆医科大学学报 ›› 2024, Vol. 49 ›› Issue (08) : 931-936. DOI: 10.13406/j.cnki.cyxb.003563
综述

功能性近红外光谱在抑郁症诊断及治疗监测中的临床应用

作者信息 +

Clinical application of functional near-infrared spectroscopy in the diagnosis and treatment monitoring of major depressive disorder

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摘要

抑郁症发病率快速上升，具有高致残率、高死亡率及高漏诊率等特点，目前抑郁症的诊断主要依靠临床症状和各种评定量表，缺乏客观的生物学指标。功能性近红外光谱是一种新兴无创的脑功能成像技术，2009年作为辅助诊断的生物学指标获得批准用于精神疾病的鉴别，尤其是在抑郁症中其临床应用和研究快速增加。本文将从功能性近红外光谱在诊断抑郁症、判断疾病程度、监测治疗反应及在青少年抑郁症中的应用方面进行全面的综述，为临床研究和运用提供指导。

Abstract

The incidence rate of major depressive disorder（MDD） is rising rapidly，with the characteristics of high disability rate，high mortality rate，and high missed diagnosis rate. At present，the diagnosis of MDD mainly relies on clinical symptoms and various rating scales，and there is still a lack of objective biological indicators. Functional near-infrared spectroscopy（fNIRS） is an emerging noninvasive brain functional imaging technique，and in 2009，it was approved for the identification of mental illnesses as a biological indicator for auxiliary diagnosis，especially in MDD，showing rapid increases in clinical application and studies. This article comprehensively reviews the application of fNIRS in diagnosing MDD，assessing disease severity，and monitoring treatment response，as well as its application in adolescent depression，so as to provide guidance for clinical research and application.

关键词

功能性近红外光谱 / 抑郁症 / 诊断 / 监测

Key words

functional near-infrared spectroscopy / major depressive disorder / diagnosis / monitoring

中图分类号

R749.4

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李夏颖 , 洪素 , 况利. 功能性近红外光谱在抑郁症诊断及治疗监测中的临床应用. 重庆医科大学学报. 2024, 49(08): 931-936 https://doi.org/10.13406/j.cnki.cyxb.003563
Li Xiaying, Hong Su, Kuang Li. Clinical application of functional near-infrared spectroscopy in the diagnosis and treatment monitoring of major depressive disorder[J]. Journal of Chongqing Medical University. 2024, 49(08): 931-936 https://doi.org/10.13406/j.cnki.cyxb.003563

参考文献

列表( 原文顺序 | 文献年度倒序 | 文中引用次数倒序 ) 可视化分析
1
World Health Organization. Depression and other common mental disorders: Global health estimates[EB/OL].（2017-01-03）[2023-12-10].
https://www.who.int/publications/i/item/depression-global-health-estimates
本文引用 [2]
2
Ehlis AC， Schneider S， Dresler T，et al. Application of functional near-infrared spectroscopy in psychiatry[J]. NeuroImage，2014，85 Pt 1：478-488．
本文引用 [3]
3
Lim GY， Tam WW， Lu YX，et al. Prevalence of depression in the community from 30 countries between 1994 and 2014[J]. Sci Rep，2018，8（1）：2861．
本文引用 [1]
4
邓艺雯，张寅航，徐兴浩，等. 基于化学遗传的慢性应激导致抑郁症小鼠模型的构建[J]. 中山大学学报（医学科学版），2021，42（3）：346-354．
Deng YW， Zhang YH， Xu XH，et al. Establishment of chronic stress inducing depressive disorder mouse model via chemical genetics[J]. J Sun Yat Sen Univ Med Sci，2021，42（3）：346-354．
本文引用 [1]
5
Choo CC， Harris KM， Ho RC. Prediction of lethality in suicide attempts：gender matters[J]. Omega （Westport），2019，80（1）：87-103．
本文引用 [1]
6
Szanto K， Galfalvy H， Kenneally L，et al. Predictors of serious suicidal behavior in late-life depression[J]. Eur Neuropsychopharmacol，2020，40：85-98．
本文引用 [1]
7
Zhang XC， Wang X， Dong DF，et al. Persistent ventral anterior cingulate cortex and resolved amygdala hyper-responses to negative outcomes after depression remission：a combined cross-sectional and longitudinal study[J]. Biol Psychiatry，2023，93（3）：268-278．
本文引用 [1]
8
Breukelaar IA， Erlinger M， Harris A，et al. Investigating the neural basis of cognitive control dysfunction in mood disorders[J]. Bipolar Disord，2020，22（3）：286-295．
本文引用 [1]
9
Ottowitz WE， Tondo L， Dougherty DD，et al. The neural network basis for abnormalities of attention and executive function in major depressive disorder：implications for application of the medical disease model to psychiatric disorders[J]. Harv Rev Psychiatry，2002，10（2）：86-99．
本文引用 [1]
10
吴文源，魏　镜，陶明. 综合医院焦虑抑郁诊断和治疗的专家共识[J]. 中华医学杂志，2012，92（31）：2174-2181．
Wu WY， Wei J， Tao M. Expert consensus on diagnosis and treatment of anxiety and depression in general hospitals[J]. Natl Med J China，2012，92（31）：2174-2181．
本文引用 [1]
11
卢　瑾，李凌江，许秀峰. 中国抑郁障碍防治指南（第二版）解读：评估与诊断[J]. 中华精神科杂志，2017，50（3）：169-171．
Lu J， Li LJ， Xu XF. Interpretation of China’s guidelines for the prevention and treatment of depression （second edition）：evaluation and diagnosis[J]. Chin J Psychiatry，2017，50（3）：169-171．
本文引用 [1]
12
Okada G， Okamoto Y， Yamashita H，et al. Attenuated prefrontal activation during a verbal fluency task in remitted major depression[J]. Psychiatry Clin Neurosci，2009，63（3）：423-425．
本文引用 [2]
13
Meyer JH， Houle S， Sagrati S，et al. Brain serotonin transporter binding potential measured with carbon 11-labeled DASB positron emission tomography：effects of major depressive episodes and severity of dysfunctional attitudes[J]. Arch Gen Psychiatry，2004，61（12）：1271-1279．
本文引用 [1]
14
Okada F， Takahashi N， Tokumitsu Y. Dominance of the ‘nondominant’ hemisphere in depression[J]. J Affect Disord，1996，37（1）：13-21．
本文引用 [1]
15
Lai CYY， Ho CSH， Lim CR，et al. Functional near-infrared spectroscopy in psychiatry[J]. Bjpsych Adv，2017，23（5）：324-330．
本文引用 [2]
16
Scholkmann F， Kleiser S， Metz AJ，et al. A review on continuous wave functional near-infrared spectroscopy and imaging instrumentation and methodology[J]. NeuroImage，2014，85：6-27．
本文引用 [1]
17
Li RH， Hosseini H， Saggar M，et al. Current opinions on the present and future use of functional near-infrared spectroscopy in psychiatry[J]. Neurophotonics，2023，10（1）：013505．
本文引用 [1]
18
Zhang HJ， Dong WT， Dang WM，et al. Near-infrared spectroscopy for examination of prefrontal activation during cognitive tasks in patients with major depressive disorder：a meta-analysis of observational studies[J]. Psychiatry Clin Neurosci，2015，69（1）：22-33．
本文引用 [1]
19
Hanley JR， Dewick HC， Davies AD，et al. Verbal fluency in Parkinson’s disease[J]. Neuropsychologia，1990，28（7）：737-741．
本文引用 [1]
20
Yeung MK， Lin JX. Probing depression，schizophrenia，and other psychiatric disorders using fNIRS and the verbal fluency test：a systematic review and meta-analysis[J]. J Psychiatr Res，2021，140：416-435．
本文引用 [2]
21
Zuckerman H， Pan ZH， Park C，et al. Recognition and treatment of cognitive dysfunction in major depressive disorder[J]. Front Psychiatry，2018，9：655．
本文引用 [1]
22
Ismail Z， Elbayoumi H， Fischer CE，et al. Prevalence of depression in patients with mild cognitive impairment：a systematic review and meta-analysis[J]. JAMA Psychiatry，2017，74（1）：58-67．
本文引用 [1]
23
Zhang FF， Peng W， Sweeney JA，et al. Brain structure alterations in depression：Psychoradiological evidence[J]. CNS Neurosci Ther，2018，24（11）：994-1003．
本文引用 [1]
24
Rosenbaum D， Hagen K， Deppermann S，et al. State-dependent altered connectivity in late-life depression：a functional near-infrared spectroscopy study[J]. Neurobiol Aging，2016，39：57-68．
本文引用 [2]
25
Kito H， Ryokawa A， Kinoshita Y，et al. Comparison of alterations in cerebral hemoglobin oxygenation in late life depression and Alzheimer’s disease as assessed by near-infrared spectroscopy[J]. Behav Brain Funct，2014，10：8．
本文引用 [2]
26
Matsuo K， Kato T， Fukuda M，et al. Alteration of hemoglobin oxygenation in the frontal region in elderly depressed patients as measured by near-infrared spectroscopy[J]. J Neuropsychiatry Clin Neurosci，2000，12（4）：465-471．
本文引用 [1]
27
Matsuo K， Kato N， Kato T. Decreased cerebral haemodynamic response to cognitive and physiological tasks in mood disorders as shown by near-infrared spectroscopy[J]. Psychol Med，2002，32（6）：1029-1037．
本文引用 [2]
28
Matsubara T， Matsuo K， Harada K，et al. Different fronto-temporal activation during an emotional word task in patients with unipolar and bipolar depression: A functional near-infrared spectroscopy study[J]. Biological Psychiatry,2015,77（9）：S355.
本文引用 [1]
29
Matsubara T， Matsuo K， Nakashima M，et al. Prefrontal activation in response to emotional words in patients with bipolar disorder and major depressive disorder[J]. NeuroImage，2014，85 Pt 1：489-497．
本文引用 [1]
30
Nishizawa Y， Kanazawa T， Kawabata Y，et al. fNIRS assessment during an emotional stroop task among patients with depression：replication and extension[J]. Psychiatry Investig，2019，16（1）：80-86．
本文引用 [2]
31
Matsuo K， Onodera Y， Hamamoto T，et al. Hypofrontality and microvascular dysregulation in remitted late-onset depression assessed by functional near-infrared spectroscopy[J]. NeuroImage，2005，26（1）：234-242．
本文引用 [1]
32
Suto T， Fukuda M， Ito M，et al. Multichannel near-infrared spectroscopy in depression and schizophrenia：cognitive brain activation study[J]. Biol Psychiatry，2004，55（5）：501-511．
本文引用 [2]
33
Kondo A， Shoji Y， Morita K，et al. Characteristics of oxygenated hemoglobin concentration change during pleasant and unpleasant image-recall tasks in patients with depression：comparison with healthy subjects[J]. Psychiatry Clin Neurosci，2018，72（8）：611-622．
本文引用 [1]
34
Kinoshita S， Kanazawa T， Kikuyama H，et al. Clinical application of DEX/CRH test and multi-channel NIRS in patients with depression[J]. Behav Brain Funct，2016，12（1）：25．
本文引用 [1]
35
Shimodera S， Imai Y， Kamimura N，et al. Near-infrared spectroscopy of bipolar disorder may be distinct from that of unipolar depression and of healthy controls[J]. Asia Pac Psychiatry，2012，4（4）：258-265．
本文引用 [1]
36
Takizawa R， Fukuda M， Kawasaki S，et al. Neuroimaging-aided differential diagnosis of the depressive state[J]. NeuroImage，2014，85 Pt 1：498-507．
本文引用 [1]
37
Uemura K， Shimada H， Doi T，et al. Depressive symptoms in older adults are associated with decreased cerebral oxygenation of the prefrontal cortex during a trail-making test[J]. Arch Gerontol Geriatr，2014，59（2）：422-428．
本文引用 [1]
38
Wang JJ， Lv B， Quan WX，et al. Right fronto-temporal activation differs between Chinese first-episode and recurrent Major Depression Disorders during a verbal fluency task：a near-infrared spectroscopy study[J]. Psychiatry Res Neuroimaging，2017，264：68-75．
本文引用 [1]
39
Akiyama T， Koeda M， Okubo Y，et al. Hypofunction of left dorsolateral prefrontal cortex in depression during verbal fluency task：a multi-channel near-infrared spectroscopy study[J]. J Affect Disord，2018，231：83-90．
本文引用 [1]
40
Tsujii N， Mikawa W， Akashi H，et al. Right temporal activation differs between melancholia and nonmelancholic depression：a multichannel near-infrared spectroscopy study[J]. J Psychiatr Res，2014，55：1-7．
本文引用 [3]
41
Liu XM， Sun GX， Zhang XQ，et al. Relationship between the prefrontal function and the severity of the emotional symptoms during a verbal fluency task in patients with major depressive disorder：a multi-channel NIRS study[J]. Prog Neuropsychopharmacol Biol Psychiatry，2014，54：114-121．
本文引用 [3]
42
Pu SH， Nakagome K， Yamada T，et al. Suicidal ideation is associated with reduced prefrontal activation during a verbal fluency task in patients with major depressive disorder[J]. J Affect Disord，2015，181：9-17．
本文引用 [1]
43
Tsujii N， Mikawa W， Tsujimoto E，et al. Reduced left precentral regional responses in patients with major depressive disorder and history of suicide attempts[J]. PLoS One，2017，12（4）：e0175249．
本文引用 [1]
44
Nishida M， Kikuchi S， Matsumoto K，et al. Sleep complaints are associated with reduced left prefrontal activation during a verbal fluency task in patients with major depression：a multi-channel near-infrared spectroscopy study[J]. J Affect Disord，2017，207：102-109．
本文引用 [1]
45
Tsujii N， Mikawa W， Tsujimoto E，et al. Relationship between prefrontal hemodynamic responses and quality of life differs between melancholia and non-melancholic depression[J]. Psychiatry Res Neuroimaging，2016，253：26-35．
本文引用 [1]
46
Pu SH， Nakagome K， Yamada T，et al. The relationship between the prefrontal activation during a verbal fluency task and stress-coping style in major depressive disorder：a near-infrared spectroscopy study[J]. J Psychiatr Res，2012，46（11）：1427-1434．
本文引用 [1]
47
Tomioka H， Yamagata B， Kawasaki S，et al. A longitudinal functional neuroimaging study in medication-naïve depression after antidepressant treatment[J]. PLoS One，2015，10（3）：e0120828．
本文引用 [2]
48
Yamagata B， Yamanaka K， Takei Y，et al. Brain functional alterations observed 4-weekly in major depressive disorder following antidepressant treatment[J]. J Affect Disord，2019，252：25-31．
本文引用 [1]
49
Ohtani T， Nishimura Y， Takahashi K，et al. Association between longitudinal changes in prefrontal hemodynamic responses and social adaptation in patients with bipolar disorder and major depressive disorder[J]. J Affect Disord，2015，176：78-86．
本文引用 [1]
50
Pu SH， Nakagome K， Yamada T，et al. Prefrontal activation predicts social functioning improvement after initial treatment in late-onset depression[J]. J Psychiatr Res，2015，62：62-70．
本文引用 [1]
51
Hirano J， Takamiya A， Yamagata B，et al. Frontal and temporal cortical functional recovery after electroconvulsive therapy for depression：a longitudinal functional near-infrared spectroscopy study[J]. J Psychiatr Res，2017，91：26-35．
本文引用 [2]
52
Shinba T， Kariya N， Matsuda S，et al. Increase of frontal cerebral blood volume during transcranial magnetic stimulation in depression is related to treatment effectiveness：a pilot study with near-infrared spectroscopy[J]. Psychiatry Clin Neurosci，2018，72（8）：602-610．
53
Eschweiler GW， Wegerer C， Schlotter W，et al. Left prefrontal activation predicts therapeutic effects of repetitive transcranial magnetic stimulation（rTMS） in major depression[J]. Psychiatry Res，2000，99（3）：161-172．
54
Downey D， Brigadoi S， Trevithick L，et al. Frontal haemodynamic responses in depression and the effect of electroconvulsive therapy[J]. J Psychopharmacol，2019，33（8）：1003-1014．
本文引用 [2]
55
Feng K， Shen CY， Ma XY，et al. Effects of music therapy on major depressive disorder：a study of prefrontal hemodynamic functions using fNIRS[J]. Psychiatry Res，2019，275：86-93．
本文引用 [1]
56
Aoki J， Iwahashi K， Ishigooka J，et al. Evaluation of cerebral activity in the prefrontal cortex in mood[affective]disorders during animal-assisted therapy（AAT） by near-infrared spectroscopy（NIRS）：a pilot study[J]. Int J Psychiatry Clin Pract，2012，16（3）：205-213．
本文引用 [1]
57
Usami M， Iwadare Y， Kodaira M，et al. Near infrared spectroscopy study of the frontopolar hemodynamic response and depressive mood in children with major depressive disorder：a pilot study[J]. PLoS One，2014，9（1）：e86290．
本文引用 [1]
58
Liu XL， Cheng F， Hu SS，et al. Cortical activation and functional connectivity during the verbal fluency task for adolescent-onset depression：a multi-channel NIRS study[J]. J Psychiatr Res，2022，147：254-261．
本文引用 [1]
59
Kim S， Yoon H， Shin J，et al. Classification of fNIRS signals from adolescents with MDD in suicide high- and low-risk groups using machine learning[J]. J Affect Disord，2023，340：379-386．
本文引用 [1]
60
Liang XM， Qiao D， Ren T，et al. Neural association between cognitive function and anhedonia in adolescents with melancholic major depressive disorder：a fNIRS study[J]. J Affect Disord，2023，338：305-311．
本文引用 [1]
61
Liu XL， Cheng F， Zhuang WH，et al. Deficits in executive function in adolescent-onset depression: A multi-channel nirs study[J/OL]. （2021-06-18）[2023-12-10].
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3869639
本文引用 [1]
62
Ho CSH， Zhang MWB， Ho RCM. Optical topography in psychiatry：a chip off the old block or a new look beyond the mind-brain frontiers?[J]. Front Psychiatry，2016，7：74．
本文引用 [1]
63
Kirilina E， Jelzow A， Heine A，et al. The physiological origin of task-evoked systemic artefacts in functional near infrared spectroscopy[J]. NeuroImage，2012，61（1）：70-81．
本文引用 [1]
64
Caldwell M， Scholkmann F， Wolf U，et al. Modelling confounding effects from extracerebral contamination and systemic factors on functional near-infrared spectroscopy[J]. NeuroImage，2016，143：91-105．
本文引用 [1]

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国家自然科学基金资助项目(81971286)

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