药理学作为高等医学院校临床医学、药学等专业的核心基础课程，是连接基础医学、药学与临床医学的重要桥梁，学生普遍反映药理学内容抽象、知识点繁多，难学难记，学习过程中容易产生畏难情绪等问题，传统教学模式难以满足学生学习需求。本研究基于成果导向教育理念，围绕新时代新质生产力背景下医药学人才培养的要求，通过线上线下有机结合的药理学混合式交互教学模式，均衡使用多种教学方法，加强基础医学与临床医学有效紧密结合，助力人才培养质量提升；培养学生从低阶程序性知识的吸收，提升到高阶程序性知识和策略性知识的吸收，促进学生构建以临床思维为基础的药理学知识体系，将药理学知识活学、活用。该模式有效弥补传统教学的不足，培养学生建立了初步的临床思维和科研思维，显著提高学生的自主学习能力和学习效果，促进学生综合素质能力的提升。

Pharmacology, as a core basic course of clinical medicine, pharmacy and other majors in medical colleges and universities, is an important bridge connecting basic medicine, pharmacy and clinical medicine. Students generally report that pharmacology is abstract in content, has numerous knowledge points, is difficult to learn and remember, and is prone to problems such as fear of difficulties in the learning process. Traditional teaching models are difficult to meet students' learning needs. This study is based on the concept of outcome-based education (OBE), focusing on the requirements of medical personnel training under the background of new quality productivity in the new era, through the online and offline organic combination of pharmacology mixed interactive teaching mode, balanced use of a variety of teaching methods, strengthen the effective and close integration of basic medicine and clinical medicine, and help improve the quality of talent training; train students from the absorption of low-level procedural knowledge to the absorption of high-level procedural knowledge and strategic knowledge, and promote students to build a pharmacological knowledge system based on clinical thinking and integrates it into their minds and hearts. This model effectively compensates for the shortcomings of traditional teaching, cultivates students' preliminary clinical thinking and scientific research thinking, significantly improves students' self-learning ability and learning effectiveness, and promotes the improvement of students' comprehensive quality and ability.