目的 比较建构主义学习理论下项目驱动式教学法在本科护理学专业基础护理学课程教学中的应用效果，探索对学生自主学习能力及人文关怀能力的影响。 方法 选择新疆医科大学护理学院本科护理学专业2022级4个班共193名学生为研究对象，其中试验组97名，对照组96名，试验组采用建构主义理念下项目驱动式教学，对照组采用研讨式5W案例教学法（What，Why，Where，Way，When）进行教学。 结果 两组学生理论成绩差异无统计学意义（t=1.35，P=0.090）；试验组学生实践成绩高于对照组，差异有统计学意义（t=8.31，P＜0.01）；线上平台学习得分试验组高于对照组，差异有统计学意义（t=6.95，P＜0.01）。试验组学生自主学习能力高于对照组，差异有统计学意义（t=3.72，P＜0.01）；试验组人文关怀能力高于对照组，差异有统计学意义（t=-2.38，P＜0.01）。 结论 在基础护理学课程应用建构主义学习理论下项目驱动式教学有助于提升学生成绩，且有利于提升自主学习学生能力和人文关怀能力。

Objective To compare the application effect of project-driven teaching method under the constructivism learning theory in the basic nursing classroom teaching of undergraduate nursing majors, and to explore the impact on students' autonomous learning ability and humanistic caring ability. Methods A total of 193 students from 4 classes of 2022 majoring in nursing from School of Nursing, Xinjiang Medical University were selected as the research objects, 97 in the experimental group and 96 in the control group. The experimental group adopted project-driven teaching under the constructivism concept. The control group was taught with the investigatory 5W case teaching method (What, Why, Where, Way, When). Results There was no significant difference between the two groups (t=1.35, P=0.09). The practical performance of test group was higher than that of control group, and the difference was statistically significant (t=8.31, P＜0.01). The result of process evaluation of test group was higher than that of control group, and the difference was statistically significant (t=6.95, P＜0.01). The autonomous learning ability of test group was higher than that of control group, and the difference was statistically significant (t=3.72, P＜0.01). The humanistic caring ability of experimental group was higher than that of control group, and the difference was statistically significant (t=-2.38, P＜0.01). Conclusion The project-driven teaching under the constructivism learning theory in basic nursing curriculum is conducive to improving students' academic performance, autonomous learning ability and humanistic care ability.