精神障碍类疾病神经调控新进展

张新, 吴精川, 陈亮

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重庆医科大学学报 ›› 2024, Vol. 49 ›› Issue (05) : 643-648. DOI: 10.13406/j.cnki.cyxb.003484
精神疾病及功能性神经疾病的治疗

精神障碍类疾病神经调控新进展

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New advances in neuromodulation for mental disorders

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摘要

精神障碍类疾病是一类涉及认知、情感、思维和行为的疾病，其临床表现各异，致病机制复杂，病因尚未被彻底阐明，目前仍无有效的针对性治疗方案，是当前医学领域的难点之一。近年研究结果表明，以电、磁、光、声为基础开发的新型神经调控手段可以有效的治疗或缓解各类药物难治性精神类疾病的临床症状。因此本文将聚焦于总结和回顾各类新型神经调控手段的研发与应用进展，为精神障碍类疾病治疗方案的更新提供新思路。

Abstract

Mental disorders encompass a spectrum of conditions involving disturbances in cognition，emotion，thinking，and behavior， with diverse clinical manifestations and complex pathogenic mechanisms. The etiology of these disorders remains unclear，and there are still no effective targeted treatment regimens，posing a significant challenge in the field of medicine. Recent research findings have shown that novel neuroregulation techniques based on electricity，magnetism，light，and sound can effectively treat or alleviate the clinical symptoms of various medically intractable mental disorders. Therefore，this article summarizes and reviews the advances in the development and application of various novel neuroregulation techniques，so as to provide new insights for updating the treatment regimens for mental disorders.

关键词

精神障碍 / 神经调控 / 脑深部电刺激 / 迷走神经刺激 / 经颅磁刺激

Key words

mental disorders / neuromodulation / deep brain stimulation / vagus nerve stimulation / transcranial magnetic stimulation

中图分类号

R749

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张新 , 吴精川 , 陈亮. 精神障碍类疾病神经调控新进展. 重庆医科大学学报. 2024, 49(05): 643-648 https://doi.org/10.13406/j.cnki.cyxb.003484
Zhang Xin, Wu Jingchuan, Chen Liang. New advances in neuromodulation for mental disorders[J]. Journal of Chongqing Medical University. 2024, 49(05): 643-648 https://doi.org/10.13406/j.cnki.cyxb.003484

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国家自然科学基金面上资助项目(82272116)

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