目的 探讨护理专业新生宿舍人际关系对抑郁情绪的影响，为护理专业新生抑郁情绪倾向的心理疏导提供依据。 方法 于2023年1－2月期间，利用电子问卷开展宿舍人际关系对抑郁情绪的影响调查，以北京卫生职业学院护理专业新生作为研究对象，面向324名学生开展调查，利用SPSS 22.0数据统计软件完成数据处理与分析，确定护理专业新生宿舍人际关系对抑郁情绪的影响。 结果 不同抑郁情绪倾向下护理专业新生宿舍人际关系中的群体认知（F=3.488，P=0.019）、言语沟通（F=4.224，P=0.024）、扰他行为（F=4.865，P=0.009）、共享行为（F=5.220，P=0.002）、个体特征（F=5.021，P=0.003）差异均有统计学意义，宿舍人际关系对抑郁情绪倾向有影响，护理专业新生的抑郁情绪得分在人口特征因素中的生源地比较，差异具有统计学意义（t=0.361，P=0.035）。 结论 护理专业新生宿舍人际关系对抑郁情绪倾向有影响，学校相关部门在宿舍管理过程中，要重视抑郁情绪倾向学生的识别与疏导，早期发现抑郁情绪，对其抑郁情绪引发原因进行判断后，关注护生宿舍人际关系情况，通过宿舍人际关系改善，提升她们的心理健康水平。

Objective To explore the influence of dormitory interpersonal relationship on depression of nursing freshmen, and to provide basis for psychological counseling of depressive tendencies in nursing freshmen. Methods An electronic questionnaire was used to investigate the influence of dormitory interpersonal relationship on depression from January to February 2023. Taking nursing freshmen in a college as the research object, a survey was conducted on 324 students. Data were processed and analyzed by SPSS22.0 to determine the influence of dormitory interpersonal relationship on depression of nursing freshmen. Results There were significant differences of group cognition (F=3.488, P=0.019), verbal communication (F=4.224, P=0.024), disturbing behavior (F=4.865, P=0.009), sharing behavior (F=5.220, P=0.002), individual characteristics (F=5.021, P=0.003) in the dormitory interpersonal relationship of nursing freshmen among different depressive tendencies. The dormitory interpersonal relationship has a significant impact on depressive tendencies. The depression scores of nursing freshmen show significant differences in the factor of student origin (t=0.361, P=0.035) of demographic characteristics. Conclusion The dormitory interpersonal relationship has a significant impact on depressive tendencies of nursing freshmen. Relevant departments of the college should pay attention to the identification and guidance of students with depressive tendencies in the management of dormitory, detect depressive mood early, judge the causes of depression, pay attention to dormitory interpersonal relationship of nursing students, and improve their mental health level through improving dormitory interpersonal relationship.