Based on the problems and deficiencies in the teaching process of pharmaceutics experiment course, and in order to meet the needs of training innovative pharmaceutical talents in the new era, the teaching model of "guide - learn - research" has been thoroughly reformed in three progressive learning stages: the pre-study of questions raised by teachers before the experiment, the student-centered independent learning during the experiment and the in-depth study of the application of the experiment content in practice after the experiment. Through the process of applying theoretical knowledge to experimental courses and fully consolidating what is learned from experimental courses in practice, this model aims to cultivate innovative pharmaceutical talents with both creativity and practical skills, suited to the development needs of the pharmaceutical industry in the new era.