病理解剖学基础是介于基础医学与临床医学之间的一门课程，在医学药学基础教育中占有重要地位。本文探索线上线下混合式教学模式在病理解剖学基础教学中的应用。课程完善了教学资源，包括课前预习视频、病理解剖学基础案例分析库、课程思政教学案例库、数字化切片资源库和病理解剖学基础题库等。引入案例教学法、融入课程思政教学、翻转课堂等教学方法，设计和实施了符合线上线下混合课程的评价考核方式，为进一步提高教学质量奠定基础

Basic Pathological Anatomy is a course that lies between basic medicine and clinical medicine, and plays an important role in the basic education of medicine and pharmacy. This paper explores the application of online and offline hybrid teaching mode in this course. Teaching resources have been improved, including pre-class study videos, pathology case analysis library, ideological and political education case library, digital slicing resource library, and a question bank for Basic Pathological Anatomy. Case teaching method, ideological and political education, flipped classroom and other teaching methods have been introduced. In addition, we have designed and implemented evaluation and assessment methods that are suitable for the hybrid courses, laying the foundation for further improving teaching quality.