党参提取物对断奶仔猪生长性能、血清生化指标和肠道健康的影响

廖维连

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养殖与饲料 ›› 2024, Vol. 23 ›› Issue (09) : 10-16. DOI: 10.13300/j.cnki.cn42-1648/s.2024.09.003
饲料营养

党参提取物对断奶仔猪生长性能、血清生化指标和肠道健康的影响

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Effects of extract from Codonopsis pilosula on the growth performance, biochemical indexes in serum, and intestinal health of weaned piglets

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摘要

目的 研究党参提取物对促进断奶仔猪生长及改善其肠道健康的影响,为改善仔猪健康和提高生猪养殖效益提供依据。 方法 选取21日龄性别、品种相同的三元断奶仔猪24头,随机分为3组,每组8个重复。对照组饲喂基础日粮,试验组分为低剂量组和高剂量组,分别在基础日粮中添加0.1%和0.2%的党参提取物,试验期间对其生长性能、血清生化指标和小肠结构进行测定。 结果 与对照组相比,党参提取物的低剂量组和高剂量组仔猪的平均日增质量分别显著提高了11.28%和20.00%,料重比分别显著降低了6.82%和9.85%;低剂量组和高剂量组的断奶仔猪血清谷草转氨酶活性分别显著降低了36.28%和39.24%,乳酸脱氢酶活性分别显著降低了28.07%和35.22%;试验组的谷草/谷丙比值显著降低。饲粮中添加党参提取物显著提高了断奶仔猪十二指肠、空肠和回肠的绒毛高度,并显著增加了十二指肠和空肠的绒隐比;但对断奶仔猪脏器指数无显著影响。 结论 在饲粮中添加党参提取物能够显著改善断奶仔猪的生长性能,减少肝脏损伤,并促进肠道健康。其中,以0.2%的添加比例效果最佳。

Abstract

Objectives The effects of extract from Codonopsis pilosula on promoting the growth and intestinal health of weaned piglets were studied to provide a basis for improving the health of piglets and enhancing the efficiency of farming pigs. Methods 24 weaned piglets of the same sex and breed at 21 days of age were selected and randomly divided into 3 groups, with 8 replicates in each group. The control group was fed a basic diet, while the experimental groups were divided into a low-dose group and a high-dose group, with 0.1% and 0.2% extract from Codonopsis pilosula added to the basic diet, respectively. The growth performance, biochemical indexes in serum and the structure of small intestine were measured during the experiment. Results The average daily gain of weight in piglets in the low-dose and high-dose groups of extract from Codonopsis pilosula significantly increased by 11.28% and 20.00%, and the ratio of feed to weight significantly decreased by 6.82% and 9.85% compared with the control group. The activity of alanine aminotransferase in the serum of weaned piglets in the low-dose group and high-dose group significantly decreased by 36.28% and 39.24%, and the activity of lactate dehydrogenase significantly decreased by 28.07% and 35.22%. The ratio of glutamic straw to grain C in the experimental group decreased significantly. The addition of extract from Codonopsis pilosula to the feed significantly increased the villus height of the duodenum, jejunum, and ileum, and the ratio of pile to hide in duodenum and jejunum of weaned piglets. But it has no significant effect on the organ index of weaned piglets. Conclusions Adding extract from Codonopsis pilosula to the feed can significantly improve the growth performance, reduce liver damage, and promote intestinal health of weaned piglets. The best effect was achieved with a 0.2% addition ratio.

关键词

党参提取物 / 断奶仔猪 / 生长性能 / 血清生化 / 肠道健康 / 日增质量 / 料重比

Key words

extract from Codonopsis pilosula / weaned piglets / growth performance / biochemistry in serum / intestinal health / daily gain of weight / ratio of feed to weight

中图分类号

S828.5

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导出引用
廖维连. 党参提取物对断奶仔猪生长性能、血清生化指标和肠道健康的影响. 养殖与饲料. 2024, 23(09): 10-16 https://doi.org/10.13300/j.cnki.cn42-1648/s.2024.09.003
LIAO Weilian. Effects of extract from Codonopsis pilosula on the growth performance, biochemical indexes in serum, and intestinal health of weaned piglets[J]. Animals Breeding and Feed. 2024, 23(09): 10-16 https://doi.org/10.13300/j.cnki.cn42-1648/s.2024.09.003

参考文献

1
敖弟修. 断奶仔猪的生理特点及饲养管理方法[J]. 广东蚕业202458(3):64-66.
2
TANG X, XIONG K, FANG R, et al. Weaning stress and intestinal health of piglets:a review [J/OL]. Frontiers in immunology202213:1042778[2024-05-09].
3
刘静凤, 刘春秀, 蒋道玉, 等. 健康与腹泻断奶仔猪肠道菌群组成与差异比较分析 [J]. 饲料工业20243(2):1-20.
4
BAI R, ZHANG Y, JIA X, et al. Isolation, characterization and immunomodulatory activity of oligosaccharides from Codonopsis pilosula : a review [J/OL]. Journal of functional foods202072: 104070[2024-05-09].
5
LUAN F, JI Y, PENG L, et al. Extraction, purification, structural characteristics and biological properties of the polysaccharides from Codonopsis pilosula: a review [J/OL]. Carbohydr polym2021261: 117863[2024-05-09].
6
GONG Z, ZHANG S, GU B, et al. Codonopsis pilosula polysaccharides attenuate Escherichia coli-induced acute lung injury in mice [J]. Food Funct202213(15): 7999-8011.
7
KELLY D, O'BRIEN J J, MCCRACKEN K J. Effect of creep feeding on the incidence, duration and severity of post-weaning diarrhoea in pigs [J]. Research in veterinary science199049(2): 223-228.
8
金娜, 邹闻书, 高倩, 等. 枸芪多糖对育肥猪生长性能、胴体性状和肠道组织形态的影响 [J]. 北京农学院学报202035(1):55-59.
9
戴国能. 日粮中添加党参多糖对断奶仔猪生长性能、血清生化和免疫指标的影响 [J]. 中国畜禽种业202420(3):77-81.
10
隋奉桐, 陈静, 马旭东, 等. 党参多糖对断奶仔猪生长性能、血清免疫指标及抗氧化指标的影响 [J]. 饲料工业202445(7):38-42.
11
王广. 党参多糖对肠道菌群失调小鼠的调整作用机制的初步研究 [D].佳木斯: 佳木斯大学, 2010.
12
宋克玉, 江振友, 严群超, 等. 党参及茯苓对小鼠肠道菌群调节作用的实验研究[J]. 中国临床药理学杂志201127(2):142-145.
13
袁瑞瑛, 普珍, 王敏竹, 等. 藏党参提取物对酵母膏联合氧嗪酸钾致高尿酸血症小鼠的保护作用研究 [J]. 中医药导报202228(10): 6-11.
14
LI N, YANG C, XIA J, et al. Molecular mechanisms of Codonopsis pilosula in inhibiting hepatocellular carcinoma growth and metastasis [J/OL]. Phytomedicine : international journal of phytotherapy and phytopharmacology2024128: 155338[2024-05-09].
15
SU Q, HUO J, WANG Y, et al. The obesity amelioration effect in high-fat-diet fed mice of a homogeneous polysaccharide from Codonopsis pilosula [J/OL]. Molecules202227(16):5348[2024-05-09].
16
HU N, GAO Z, CAO P, et al. Uniform and disperse selenium nanoparticles stabilized by inulin fructans from Codonopsis pilosula and their anti-hepatoma activities [J]. Int J Biol Macromol2022203:105-115.
17
LIU C, CHEN J, LI E, et al. The comparison of antioxidative and hepatoprotective activities of Codonopsis pilosula polysaccharide (CP) and sulfated CP [J]. Int Immunopharmacol201524(2):299-305.
18
MENG X, KUANG H, WANG Q, et al. A polysaccharide from Codonopsis pilosula roots attenuates carbon tetrachloride-induced liver fibrosis via modulation of TLR4/NF-κB and TGF-β1/Smad3 signaling pathway [J/OL]. International immunopharmacology2023119:110180[2024-05-09].
19
TANG X, XIONG K, FANG R, et al. Weaning stress and intestinal health of piglets:a review [J/OL]. Frontiers in immunology202213: 1042778[2024-05-09].
20
ZHENG L, DUARTE M E, SEVAROLLI LOFTUS A, et al. Intestinal health of pigs upon weaning:challenges and nutritional intervention [J/OL]. Frontiers in veterinary science20218:628258[2024-05-09].
21
邬昆富, 王悦, 谢艺理, 等. 三七茎叶提取物对断奶仔猪生长性能、血清生化指标和肠道健康的影响 [J]. 饲料研究2024(6):26-30.
22
ZOU Y, YAN H, LI C, et al. A pectic polysaccharide from Codonopsis pilosula alleviates inflammatory response and oxidative stress of aging mice via modulating intestinal microbiota-related gut-liver axis [J/OL]. Antioxidants (Basel)202312(9):1781[2024-05-09].
23
CAO L, DU C, ZHAI X, et al. Codonopsis pilosula polysaccharide improved spleen deficiency in mice by modulating gut microbiota and energy related metabolisms [J/OL]. Front pharmacol202213:862763[2024-05-09].
24
TANG S, LIU W, ZHAO Q, et al. Combination of polysaccharides from Astragalus membranaceus and Codonopsis pilosula ameliorated mice colitis and underlying mechanisms [J/OL]. Journal of ethnopharmacology2021264: 113280[2024-05-09].
25
LIU S, XIAO G, WANG Q, et al. Effects of dietary Astragalus membranaceus and Codonopsis pilosula extracts on growth performance, antioxidant capacity, immune status, and intestinal health in broilers [J/OL]. Front Vet Sci202310: 1302801[2024-05-09].
26
ZOU Y F, LI C Y, FU Y P, et al. Restorative effects of inulin from Codonopsis pilosula on intestinal mucosal immunity, anti-inflammatory activity and gut microbiota of immunosuppressed mice [J/OL]. Frontiers in pharmacology202213: 786141[2024-05-09].
27
ZOU Y F, ZHANG Y Y, FU Y P, et al. A polysaccharide isolated from Codonopsis pilosula with immunomodulation effects both in vitro and in vitro [J/OL]. Molecules (Basel, Switzerland)201924(20):3632[2024-05-09].
28
ZHENG Y S, WU Z S, NI H B, et al. Codonopsis pilosula polysaccharide attenuates cecal ligation and puncture sepsis via circuiting regulatory T cells in mice [J]. Shock (Augusta, Ga)201441(3): 250-255.
29
BAI R B, ZHANG Y J, FAN J M, et al. Immune-enhancement effects of oligosaccharides from Codonopsis pilosula on cyclophosphamide induced immunosuppression in mice [J]. Food & function202011(4):3306-3315.

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国家自然科学基金项目(NSFC31972729)

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