
血清ALP检测在犬肿瘤预后诊断的应用研究
陈丽玲, 陈丽雄, 郭艳, 姚璐, 徐彦琼, 刘汝文
血清ALP检测在犬肿瘤预后诊断的应用研究
Application of serum ALP detection in the prognosis of canine tumors
目的 探讨血清中ALP测定对犬肿瘤性质的诊断价值研究。 方法 选取2020年6月—2023年6月收集的犬肿瘤病例共20例,分病患(试验组)与正常(对照组),根据视诊、触诊,采用微纳芯全自动动物生化仪测定数据,并进行回顾性分析,再结合X射线透视图分析肿瘤部位和游离状态。 结果 试验组血清ALP的含量比对照组高4~5倍,明显高于对照组(P<0.01);X射线透视图显示游离程度不高,粘黏深度不清,肿瘤转移严重,疑似恶性肿瘤,并且预后不良。 结论 犬肿瘤患者的预后判断中,血清ALP的检测有较强的诊断价值,可在小动物临床上进一步推广与应用。
Objectives The significance of measuring serum ALP for diagnosing the nature of canine tumors was investigated. Methods A total of 20 canine tumor cases collected from June 2020 to June 2023 were divided into two groups including the patients (experimental group) and the normal (control group). Data were measured and retrospectively analyzed with a micro nano core in the fully automatic animal biochemical instrument based on visual examination and palpation. The site and free state of tumor was characterized with images of X-ray fluoroscopy. Results The content of serum ALP in the experimental group was 4-5 times higher than that in the control group, with significant difference (P<0.01). The results of X-ray fluoroscopy showed that there was a low degree of detachment, unclear depth of adhesion, severe metastasis of tumor, indicating that the tumor is malignant and the prognosis is poor. Conclusions The detection of serum ALP has strong diagnostic value in judging the prognosis of canine tumor patients, and can be further promoted and applied in the clinical practice of small animals.
alkaline phosphatase / tumor / pet dog / prognosis
S858.292
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王晶晶, 刘琛, 秦艳茹. 血清碱性磷酸酶、癌胚抗原、糖类抗原19-9联合检测对胃癌骨转移的诊断价值[J]. 癌症进展, 2020,18(7):731-734.
|
6 |
|
7 |
|
8 |
|
9 |
冯晓雷, 吴俊毅. 碱性磷酸酶在骨肿瘤诊断中的价值[J]. 中国肿瘤临床与康复, 2016,23(8):967-969.
|
10 |
中国抗癌协会肝癌专业委员会, 中华医学会肝病学分会肝癌学组, 中国抗癌协会病理专业委员会, 等. 原发性肝癌规范化病理诊断指南(2015 年版)[J]. 中华肝胆外科杂志, 2015,21(3):145-151.
|
11 |
杜江标, 崔英, 梁新强, 等. 多种肿瘤标志物对原发性肝癌的诊断价值[J]. 广西医科大学学报, 2020,37(12):2210-2214.
|
12 |
张杨, 项舟弘, 段爱华. 原发性肝癌早期诊断中四种肿瘤标志物检验的准确性分析[J]. 中国肿瘤临床与康复, 2020,27(8):969-972.
|
13 |
颜朗, 严俊, 何天时. 血清碱性磷酸酶及乳酸脱氢酶评价肝癌切除术后生存预后的价值[J]. 中国肿瘤外科杂志, 2020,12(1):37-40.
|
14 |
高鹏飞, 杨豪俊. 不同肿瘤标志物联合检测对原发性肝癌的诊断效能分析[J]. 海南医学院学报, 2019,25(11):858-861,866.
|
15 |
|
16 |
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