以工业级聚己内酯二醇（PCL2000）、聚酯二醇（L3035）为软段，异佛尔酮二异氰酸酯为硬段，二甲基乙二肟（DMG）为功能扩链剂，采用溶液聚合，并通过添加增黏树脂和固化剂，制备一种成本较低、可工业化的高剥离、高持黏的可生物降解聚氨酯压敏胶（PSAs），考察了多元醇比例、NCO/OH值、增黏树脂和固化剂用量等对压敏胶性能的影响。采用流变仪表征了压敏胶的黏弹性，利用对甲苯磺酸降解法监测了压敏胶的降解情况。结果表明：当PCL2000用量占多元醇总质量的17.5%、NCO/OH值为2.4、DMG用量占扩链剂总质量0.8%、增黏树脂和固化剂用量分别占压敏胶固含量的18%和0.8%时，制备的压敏胶综合性能最佳，初黏对应11#钢球，剥离力为20 N/25 mm，持黏大于100 h，压敏胶降解率大于80%。

A cost-effective industrializable biodegradable polyurethane pressure-sensitive adhesive (PSAs) with high peel strength and holding time was prepared by blending of polyurethane with tackifying resin and curing agent. The polyurethane was synthesized with industrial grade polycaprolactone diol (PCL2000) and polyester diol (L3035) as soft segments, isophorone diisocyanate as hard segments, dimethylglyoxime (DMG) as a functional chain extender via solution polymerization. The effects of polyol ratio, NCO/OH value, dosage of tackifying resin and curing agent on the adhesive performance were further investigated. The viscoelastic behaviors and biodegradability of PSAs were determined by rheological measurement and p-toluene sulfonic acid degradation method, respectively. The results show that the best comprehensive performance of the pressure-sensitive adhesive is achieved when the amount of PCL2000 accounts for 17.5% of the total mass of the polyol, the NCO/OH value is 2.4, the amount of DMG accounts for 0.8% of the total mass of the chain extender, and the amounts of tackifying resin and curing agent are 18% and 0.8% of the solid content of the pressure-sensitive adhesive, respectively. The according tacking can reach to 11# steel ball, the peel strength is 20 N/25 mm, the holding time is over than 100 h, and the degradation rate of PSAs is over than 80%.