With the evolution of the times and the continuous changes of social needs, teaching reform in higher education has become an imperative demand of the new era. This study focuses on the implementation of the spirit of craftsmanship in pharmaceutical education. It thoroughly analyzes how to systematically cultivate students’ practical skills, innovative thinking, and comprehensive qualities in pharmacy teaching practice. Drawing on detailed case studies and rigorous data, this paper aims to construct an effective teaching model that stimulates the potential of pharmacy students and enhances teaching quality. The ultimate aim is to provide insightful inspiration and operable suggestions for teaching teams and educational managers, thereby driving the reform of pharmaceutical education in universities and ensuring that higher education keeps pace with the times to meet the urgent need for high-quality pharmaceutical talent.