The traditional Chinese materia medica is a distinctive discipline, inheriting and promoting the long-standing history of traditional Chinese medicine, and is a compulsory course for cultivating the comprehensive quality of students in Chinese medicine universities. Therefore, it is particularly important to integrate ideological and political elements relating to “confidence in traditional Chinese medicine culture” into curriculum design. Approaches include enhancing cognition of traditional Chinese medicine, telling stories about it, introducing traditional preparation methods, and drawing on related historical figures and events. These should be used as entry points to optimize curriculum setup, innovate teaching methods, strengthen practical teaching, and explore innovative teaching models for the Chinese materia medica course, thus cultivating pharmacy professionals with a solid foundation in traditional Chinese medicine culture and innovative capabilities for the pharmaceutical industry.