Instrumental analysis is a compulsory fundamental course for all majors in the School of Pharmacy at our university, with approximately 500 students enrolling in the course each year. This course is difficult to understand, covers a wide range of knowledge, involves extensive theoretical contents, requires strong practical skills, and has broad applications. However, due to the dual impact of the "New College Entrance Examination" and the "Reform of College Student Training Program", two major challenges have emerged: some students have not studied chemistry in high school and thus have weak foundational knowledge; classroom teaching hours have been reduced, making traditional classroom instruction insufficient to cover the course content effectively, let alone achieving good teaching results. To address these challenges, our teaching team has designed a multi-dimensional teaching approach from five aspects to create a "Five-Full" classroom - rich in intelligence, passion, interaction, challenge and ideological and political education.