China is actively promoting the transformation from a manufacturing power to a manufacturing powerhouse and from “made in China” to “created in China”. This requires a series of reforms in the field of scientific and technological innovation in the universities such as on the engineering education concept, talent training mode, professional discipline structure. Taking the life and science base class of Shenyang Pharmaceutical University as an example, the authors explore the implementation of the "3+x" pluralistic innovative talents training program based on OBE (Outcome-Based Education) as the core of engineering education in the context of new engineering disciplines. It lays the foundation for the cultivation of cutting-edge innovative engineering talents in the field of biopharmaceuticals in the future.