The establishment of pharmaceutical talents training mode should be guided by the demand of industry, establish the mindset of new pharmacy under the new medical science, and change from focusing on scale and quantity to focusing on structure, quality, efficiency and integration between industry and education. Currently, the prominent problems faced in demand-oriented pharmaceutical talents training include relatively single talent training mode, the need to strengthen social service ability, incomplete curriculum system and serious disconnection from practical needs. In the meanwhile, the standards for talent evaluation from the demand side and supply side are not unified. In order to achieve the goal of demand-oriented pharmaceutical talents training, the author's college has implemented a series of measures in pharmaceutical talents training under the background of supply-side reform, such as strengthening the teaching staff development, reforming the student management mode, and implementing the joint training bases.