Objective To trace the historical causes of the four suspensions of the School of Pharmacy in Zhejiang University. Methods Relevant historical archives, documents and databases were consulted to research and analyze the correlations. Results In 1928, due to government restructuring of specialized schools, Zhejiang Public Pharmaceutical School ceased operation; in 1931, it was reorganized as Zhejiang Provincial Pharmaceutical Specialized School; during the Anti-Japanese war in 1939, it was discontinued to support the new university in Zhejiang Province and reorganized into the Department of Pharmacy, School of Medicine of Yingshi University due to the internal relocation of Zhejiang University; in the 1950s,there were two national adjustments to higher education institutions; in 1952, the Department of Pharmacy, School of Science of Zhejiang University was suspended and merged into the School of Pharmacy of Shanghai Medical College; in 1955, the Department of Pharmacy of Zhejiang Medical College was suspended to support the two colleges and three departments of pharmacy in China; in 1962, the Department of Pharmacy of Zhejiang Medical University stopped enrolling during the period of national natural disaster. Conclusion The four suspensions of the School of Pharmacy of Zhejiang University each have their historical significance, which can offer reference for the study of the development history of higher pharmaceutical education in China.