Guided by the goal of cultivating research-oriented talents and based on the talent training objectives of environmental science major at Shenyang Pharmaceutical University, the teaching reform of environmental chemistry experiment was conducted. A student-centered experimental teaching system with the goal of improving the students' innovative ability was established. The practices showed that students' theoretical knowledge, comprehensive ability were organically integrated. Students’ abilities of scientific research innovation, team cooperation, language expression and paper writing were fully improved. This experimental reform could lay a foundation for cultivating qualified innovative talents in environmental science.