
Advances in forensic research on fatal insulin overdose
Bian Cunhao, Wang Qi, He Xin, Li Jianbo
Advances in forensic research on fatal insulin overdose
Insulin,as an important hormone that maintains glucose homeostasis in the body,is crucial in the treatment of diabetes. In recent years,with the widespread use of exogenous insulin,there has been a constant increase in insulin overdose accidents,suicides,and homicides. The forensic diagnosis of fatal insulin overdose is extremely difficult due to the difficulties in identifying the injection site,the lack of obvious pathological signs,the rapid degradation of insulin in postmortem blood,and the large fluctuation of blood biochemistry after death. Therefore,this article reviews the causes,lethal mechanisms,pathological changes,toxicological analysis,and identification points of insulin overdose,so as to provide help for the forensic identification of fatal insulin overdose.
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