Infection rate after long-tunneled external ventricular drainage versus conventional external ventricular drainage and risk factors for intracranial infection

Wang Kai, Wang Yutao, Shen Guangjian, Ji Jianwen, Cheng Saiyu, Zhang Yundong

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Journal of Chongqing Medical University ›› 2025, Vol. 50 ›› Issue (03) : 409-415. DOI: 10.13406/j.cnki.cyxb.003659
Clinical research

Infection rate after long-tunneled external ventricular drainage versus conventional external ventricular drainage and risk factors for intracranial infection

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Abstract

Objective To investigate the difference in intracranial infection rate between long-tunneled external ventricular drainage （LTEVD） and conventional external ventricular drainage（EVD），as well as the risk factors for intracranial infection. Methods A retrospective analysis was performed for the clinical data of 45 patients who were admitted to Department of Neurology Center，The Third Affiliated Hospital of Chongqing Medical University，from January 2020 to December 2022 and underwent EVD，among whom 13 patients underwent LTEVD （LTEVD group） and 32 patients underwent conventional EVD（EVD group）. Related data were recorded for both groups，including general information，postoperative catheter-related complications，and postoperative management，to investigate the effect on reducing the rate of intracranial infection. According to the presence or absence of intracranial infection after surgery，the patients were divided into the infection group with 10 patients and non-infection group with 35 patients，and related clinical data were analyzed to investigate the risk factors for intracranial infection. Results The LTEVD group had a significantly lower secondary infection rate of catheterization days than the EVD group［2.40‰（1/417） vs. 27.19‰（9/331），P=0.009］. The duration of catheterization was 14-85 days［27.00 （22.50，36.50） days］ in the LTEVD group and 8-22 days［9.00（8.00，11.50） days］ in the EVD group，suggesting that the LTEVD group had a significantly longer duration of catheterization than the EVD group（P=0.000）. The multivariate logistic regression analysis showed that the times of cerebrospinal fluid sampling was an independent risk factor for postoperative intracranial infection in patients undergoing EVD，and the use of LTEVD was a protective factor against intracranial infection after EVD. Conclusion Compared with conventional EVD，LTEVD can safely prolong the duration of catheterization and reduce the rate of postoperative intracranial infection in patients undergoing EVD. The use of LTEVD procedure and the reduction in the times of cerebrospinal fluid sampling can reduce the risk of postoperative intracranial infection.

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drainage / cerebrospinal fluid shunts / catheter-related infections / long-tunneled external ventricular drainage / risk factors

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Wang Kai , Wang Yutao , Shen Guangjian , et al . Infection rate after long-tunneled external ventricular drainage versus conventional external ventricular drainage and risk factors for intracranial infection. Journal of Chongqing Medical University. 2025, 50(03): 409-415 https://doi.org/10.13406/j.cnki.cyxb.003659

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