非酒精性脂肪肝的检出率及其影响因素分析——基于渝西地区54067份体检数据

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Journal of Chongqing Medical University ›› 2025, Vol. 50 ›› Issue (03) : 397-402. DOI: 10.13406/j.cnki.cyxb.003650

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Abstract

Objective To investigate the detection rate of nonalcoholic fatty liver disease（NAFLD） and its influencing factors among residents in western Chongqing of China during physical examination. Methods Based on the clinical diagnostic criteria and ultrasound examination results of NAFLD，the individuals who underwent physical examination in a grade A tertiary hospital in Western Chongqing from January 1，2020 to November 30，2023 were enrolled as subjects. The methods such as the t-test，the chi-square test，and the multivariate logistic regression analysis were used to clarify the detection rate of NAFLD and its influencing factors among the individuals undergoing physical examination. Results The detection rate of NAFLD was 23.64%（12 872/54 067） among the individuals undergoing physical examination. The detection rate of NAFLD in male individuals was significantly higher than that in female individuals（39.22% vs.15.91%，χ2 =2 197.112，P<0.001）. The individuals in the age group of 50-59 years had the highest NAFLD detection rate of 33.18%，and before the age of 60 years，the detection rate of NAFLD increased with age，while after the age of 60 years，the detection rate of NAFLD decreased with age（χ2 =367.554，P<0.001），indicating the detection of NAFLD in younger populations in western Chongqing. The individuals with a body mass index indicative of overweight and obesity had a significantly higher detection rate of NAFLD than those with a body mass index indicative of emaciation and normal weight （39.39%/71.40% vs. 0.23%/9.68%，χ2 =7 644.383，P<0.001）. The multivariate logistic regression analysis showed that sex，age，body mass index，fasting blood glucose（FBG），systolic blood pressure（SBP），diastolic blood pressure（DBP），triglyceride（TG），uric acid（UA），high-density lipoprotein cholesterol（HDL-C），and low-density lipoprotein cholesterol（LDL-C） were risk factors for the detection rate of NAFLD in individuals undergoing physical examination（P<0.05），while total cholesterol （TC） was not a risk factor for the detection rate of NAFLD. Conclusion The detection rate of NAFLD is 23.64% among the individuals aged 18 years or above who undergo physical examination in Western Chongqing，and there is a relatively high incidence rate of NAFLD in the age group of 50-59 years. Male individuals and overweight or obese individuals are at a high risk of NAFLD. FBG，SBP，DBP，TG，UA，HDL-C，and LDL-C are risk factors for NAFLD，while TC is not a risk factor for NAFLD.

Key words

nonalcoholic fatty liver disease / people undergoing physical examination / detection rate / influencing factors / western Chongqing

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