Correlation between perception pain threshold and pain tolerance threshold in normal adults during electrical stimulation: a multiple linear regression analysis

Yu Ya, Li Xuewei, Tang Juntong, Qin Wanxiang, Shi Ying

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Journal of Chongqing Medical University ›› 2024, Vol. 49 ›› Issue (10) : 1125-1131. DOI: 10.13406/j.cnki.cyxb.003600
Clinical research

Correlation between perception pain threshold and pain tolerance threshold in normal adults during electrical stimulation: a multiple linear regression analysis

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Abstract

Objective To measure the levels of perception pain threshold（PTH） and pain tolerance（PTO） threshold in normal adults under electrical stimulation，to investigate related influencing factors and the correlation between PTH and PTO，and to establish the reference value ranges for PTH and PTO in normal adults. Methods Univariate linear regression analysis and multivariate linear regression analysis were used to perform a retrospective analysis of related data of the normal adults who underwent electrical stimulation tests using the somatosensory evoked potential measurement system in Department of Pain，The Southwest Hospital of Army Medical University，from October 21，2017 to May 22，2020，including pain threshold data，sex，age，occupation，education background，marriage，monthly income，and body mass index（BMI）. The reference value ranges for PTH and PTO were calculated. Results The univariate linear regression analysis showed a highly positive correlation between PTH and PTO（P<0.001）. With PTH and PTO as dependent variables，sex，age，occupation，education background，marriage，monthly income，and BMI were included in the multiple linear regression analysis as independent variables，and the results showed that sex was an influencing factor for both PTH and PTO（P<0.001），with significant differences in PTH and PTO between different sexes. PTH and PTO showed normal distribution in both male and female adults（P<0.05）. The normal distribution method showed that the 95% reference ranges of PTH and PTO were 0.051-4.388 and 1.845-13.012，respectively，in male adults and were 0.146-3.069 and 1.521-10.207，respectively，in female adults； the mean±standard deviation values of PTH and PTO were 2.219±1.224 and 7.429±8.115，respectively，in male adults and were 1.608±0.556 and 5.864±4.910，respectively，in female adults. Conclusion Female adults are more sensitive to pain than their male counterparts，and the normal value ranges of PTH and PTO in female adults are narrower than those in make adults. There is a strong positive correlation between the perception and tolerance of pain.

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pain / pain threshold / multiple linear regression / reference value / sex

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Yu Ya , Li Xuewei , Tang Juntong , et al . Correlation between perception pain threshold and pain tolerance threshold in normal adults during electrical stimulation: a multiple linear regression analysis. Journal of Chongqing Medical University. 2024, 49(10): 1125-1131 https://doi.org/10.13406/j.cnki.cyxb.003600

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