1例山羊魏氏梭菌病的调查与诊断

李亚波, 张容萍, 付航, 张海楠, 马荣安

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养殖与饲料 ›› 2025, Vol. 24 ›› Issue (05) : 53-57. DOI: 10.13300/j.cnki.cn42-1648/s.2025.05.013
疾病防控

1例山羊魏氏梭菌病的调查与诊断

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Investigation and diagnosis of one Clostridium welchii disease in goat

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摘要

目的 对云南省普洱市某山羊养殖户急性死亡的山羊进行病因调查和有效诊治,以期为山羊饲养中的疫病诊断提供参考。 方法 通过对116只羊(12月龄以上成年羊40只,6~9月龄小羊76只)进行紧急流行病学调查、现场调查、病理剖检和实验室检测,并根据结果进行综合分析和诊断。 结果 病理剖检显示,病羊肺脏、肾脏和胃肠等器官均有出血,心脏呈现心衰样变;核酸检测结果显示,5头羊样品均为魏氏梭菌核酸阳性。 结论 此次山羊发病死亡由魏氏梭菌引起,野外采食感染可能性很大。羊群在未接种三联四防疫苗的背景下因饲养管理水平低,气温降低,导致其免疫力下降,造成发病死亡。应做好饲养管理和免疫,减少雨天放牧。发现异常情况及时报告,及时隔离病羊,才能有效控制疫病的传播。

Abstract

Objectives A etiological investigation and effective diagnosis and treatment of acute deaths of goats in a goat farmer in Pu'er City, Yunnan Province, was conducted to provide references for disease diagnosis in farming goat. Methods Emergency epidemiological investigation, on-site investigation, pathological autopsy, and laboratory testing were conducted on 116 goats including 40 adult goats aged over 12 months and 76 lambs aged 6-9 months to make comprehensive analysis and diagnosis. Results The results of pathological autopsy showed that there were hemorrhages in the lungs, kidneys, and gastrointestinal tract of the sick goats, with the heart having changes similar to heart failure. The results of testing nucleic acid showed that all 5 samples of goats were positive for Clostridium welchii in nucleic acid. Conclusions The illness and death of goats this time was caused by Clostridium welchii, with a high possibility of infection from grazing in the wild. The illness and death were resulted from the low level of farming and management, the decrease in temperature, and the decline in immunity of goats without vaccination with the triple and four prevention vaccines. Proper management of farming and immunization should be implemented. Grazing on rainy days should be reduced. Early reporting of any unusual circumstances and timely isolation of sick goats are necessary to effectively control the spread of the diseases.

关键词

魏氏梭菌 / 山羊 / 现场调查 / 核酸检测 / 病理剖检

Key words

Clostridium welchii / goats / on-site investigation / testing nucleic acid / pathological autopsy

中图分类号

S858.27

引用本文

导出引用
李亚波 , 张容萍 , 付航 , . 1例山羊魏氏梭菌病的调查与诊断. 养殖与饲料. 2025, 24(05): 53-57 https://doi.org/10.13300/j.cnki.cn42-1648/s.2025.05.013
LI Yabo, ZHANG Rongping, FU Hang, et al. Investigation and diagnosis of one Clostridium welchii disease in goat[J]. Animals Breeding and Feed. 2025, 24(05): 53-57 https://doi.org/10.13300/j.cnki.cn42-1648/s.2025.05.013

参考文献

1
黄紫贝.江苏省山羊源产气荚膜梭菌毒素型、耐药性调查、毒素单抗制备及ETX致弱突变[D].扬州:扬州大学,2024.
2
ROOD J I, ADAMS V, LACEY J,et al. Expansion of the Clostridium perfringens toxin-based typing scheme[J]. Anaerobe,2018,53:5-10.
3
陈溥言.兽医传染病学[M].5版.北京:中国农业出版社,2006.
4
王水云.一例山羊疑似魏氏梭菌病的诊治[J].广西畜牧兽医202339(6):267-268.
5
岳智慧.羊毒素型产气荚膜梭菌临床症状及病理变化[J].兽医导刊2021(15):43-44.
6
杨夷平,李海利,杨帆,等.产气荚膜梭菌α毒素荧光定量PCR检测方法的建立及初步应用[J].中国动物检疫2023,40(11):95-99.
7
马晶.1例黑山羊肠毒血症的诊治[J].养殖与饲料, 2017,16(2): 67-68.
8
UZAL F A, GIANNITTI F, ASIN J. Yellow lamb disease (Clostridium perfringens type A enterotoxemia of sheep): a review[J/OL]. Animals (Basel), 2022,12(12):1590[2025-02-07].
10
3390/ani12121590.
9
MUNDAY J S, BENTALL H, ABERDEIN D,et al. Death of a neonatal lamb due to Clostridium perfringens type B in New Zealand[J]. New Zealand veterinary journal, 2020, 68(4): 242-246.
11
姜萍,林英,李颖,等.常见羊魏氏梭菌病的发生特点与防治措施[J].农业工程技术, 2023, 43(13): 98-99.
12
GOHARI I M, NAVARRO M A A., LI J,et al. Pathogenicity and virulence of Clostridium perfringens [J].Virulence,2021,12(1): 723-753.
13
DIAB S S, KINDE H, MOORE J, et al. Pathology of Clostridium perfringens type C enterotoxemia in horses[J]. Veterinary pathology, 2012, 49(2): 255-263.
14
零忠利.羊肠毒血症的中西医结合防治[J]. 养殖与饲料, 2024, 23(12): 91-93.
15
UZAL F A, SONGER J G. Diagnosis of Clostridium perfringens intestinal infections in sheep and goats[J]. J Vet Diagn Invest, 2008,20(3):253-265.

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