Research Progress of Fe3O4 Mgnetic Nanomaterials in the Medical Field

Xiao YAN, Yao XU, Jing ZHANG, Xi YUAN, Famin KE

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Journal of Southwest Medical University ›› 2025, Vol. 48 ›› Issue (1) : 105-110. DOI: 10.3969/j.issn.2096-3351.2025.01.020
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Research Progress of Fe3O4 Mgnetic Nanomaterials in the Medical Field

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Abstract

With the progression of nanotechnology， magnetic nanomaterials， especially magnetite （Fe3O4） nanoparticles， have increasingly showcased their pivotal role in the field of medicine. The Fe3O4 magnetic nanomaterials garner considerable interest from researchers due to their unique magnetic properties， superior biocompatibility， and facile surface functionalization capabilities. Under the influence of external magnetic fields， these materials demonstrate rapid and directed mobility. Furthermore， their nanoscale dimensions give rise to high specific surface areas and enhanced surface energies， which facilitate the efficient adsorption and conjugation of drug molecules and biomolecules. Moreover， the stable chemical properties and low biotoxicity of Fe3O4 magnetic nanomaterials render them highly promising for various medical applications. In biomedical research， Fe3O4 magnetic nanomaterials have been widely adopted across multiple domains and achieved notable advancements. This article presented a comprehensive overview of the research advances of Fe3O4 magnetic nanomaterials in diverse areas such as drug delivery systems， tumor hyperthermia therapy， blood purification， enzyme-catalyzed therapy， magnetic resonance imaging （MRI）， protein and nucleic acid separation and purification， and cell separation and immune analysis. It also looked forward to potential development paths and innovation points in the technology..

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Fe3O4 magnetic nanomaterials / Drug delivery systems / Tumor hyperthermia therapy / Blood purification / Enzyme-catalyzed therapy / Magnetic resonance imaging （MRI） / Protein and nucleic acid separation and purification / Cell separation / Immune analysis

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Xiao YAN , Yao XU , Jing ZHANG , et al . Research Progress of Fe3O4 Mgnetic Nanomaterials in the Medical Field. Journal of Southwest Medical University. 2025, 48(1): 105-110 https://doi.org/10.3969/j.issn.2096-3351.2025.01.020

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