The mold flow simulation technology was used to simulate the injection molding process of the filter core skeleton of the oil suction filter, and the causes of the defects such as filling and warping were analyzed and the corresponding solutions were provided. The mold cavity designtook the form of having two cavities inside a core, the raw material was selected 30% glass fiber reinforced nylon resin, and the improved scheme matched the appropriate injection molding process parameters for the filter framework. The experimental results showed that double gate and "H" runner had more advantages than single gate and "Z" runner in selecting injection type and reducing warpage of parts. In the optimization scheme, the maximum injection pressure was only 75 MPa, the filling time was only 0.94 s, and the overall deformation was 0.35 mm, which met the requirements of general product size deviation, and the optimization effect was more obvious. The simulation results of the filling process were good, and the appearance and deformation measurement results of the test pieces were qualified, which verified the feasibility of the optimization parameters.