Ethylene-octene copolymer (POE) can toughen polypropylene random (PPR). However, the type of POE and the octene concentration have a significant impact on the toughening effect of PPR. In this paper, three types of POE with different octene concentrations were blended with PPR. Through non-isothermal crystallization kinetics DSC analysis of PPR/POE blends, it was revealed that the ethylene segments in PPR and POE form a eutectic structure, leading to an increase in crystallization temperature. It can be inferred from the melt flow rate that POE with a high concentration of octene will increase the crystallization temperature of the PPR/POE blend. The reason may be that POE with a high octene concentration has strong fluidity and is more easily dispersed in the PPR/POE blend, thereby providing a better toughening effect on PPR. The mechanical property tests further confirm that the addition of POE can slightly reduce the strength of PPR, with POE containing lower octene concentration having a smaller impact on strength. Therefore, in practical applications, it is necessary to comprehensively consider the application of PPR in different directions and choose the appropriate POE.