Synthesis, Characterization and Degradable Property Study of PNIPAM Microgels Crosslinked by N,N'-Bisacrylylcystamine

XU Yuan-hang, MO Ting, LI Ming-hao, LI Ke-xin, ZHANG Shuai, LI Jia-xi, SHI Shan

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Plastics Science and Technology ›› 2024, Vol. 52 ›› Issue (12) : 8-12. DOI: 10.15925/j.cnki.issn1005-3360.2024.12.002
Theory and Research

Synthesis, Characterization and Degradable Property Study of PNIPAM Microgels Crosslinked by N,N'-Bisacrylylcystamine

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Abstract

Using N-isopropylacrylamide (NIPAM) as the monomer, ammonium persulfate (APS) as the oxidizing agent, tetramethylethylenediamine (TEMED) as the reducing agent, N,N'-bis(acryloyl) cystamine (BAC) containing reducible disulfide bonds under reductive conditions as the crosslinking agent, and dimethylformamide (DMF) as the solvent for dissolving BAC, the study successfully prepared BAC-crosslinked poly(N-isopropylacrylamide) (PNIPAM) microgels through a soap-free emulsion polymerization method, utilizing the redox initiation system of APS and TEMED. The FTIR test showed that the microgels contained disulfide bonds. The product microgels were observed to be regular spheres with submicron dimensions by TEM. The microgels were observed to be significantly temperature-sensitive by DLS, with the volumetric phase-transition temperatures (VPTT) around 29.1 ℃. The BAC-crosslinked PNIPAM microgels in aqueous solution of the reductant dithiothreitol (DTT) showed an obvious degradation property, and the larger the concentration of DTT, the faster and greater the degradation of the microgel.

Key words

Soap-free emulsion polymerization / Poly(N-isopropyl acrylamide) / Temperature sensitivity / Disulfide bonds / Degradable microgel

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XU Yuan-hang , MO Ting , LI Ming-hao , et al . Synthesis, Characterization and Degradable Property Study of PNIPAM Microgels Crosslinked by N,N'-Bisacrylylcystamine. Plastics Science and Technology. 2024, 52(12): 8-12 https://doi.org/10.15925/j.cnki.issn1005-3360.2024.12.002

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