PDF(581 KB)
Influence of Industrial Production on Purity of Glycolide
WANG Fa-ting, BAI Wen-juan
PDF(581 KB)
PDF(581 KB)
Influence of Industrial Production on Purity of Glycolide
The main synthesis method of polyglycolic acid (PGA) is to use high-purity glycolide for ring-opening polymerization. Due to the special material state of the intermediate product, glycolide, in the production process, and its relatively reactive chemical nature, it is highly prone to react with water to form acidic substances. It is also susceptible to degradation reactions under the influence of temperature, which makes it challenging to obtain high-purity polymer-grade glycolide in industrial production. During the purification of glycolide through solvent recrystallization, acids and water are the main impurities affecting the purity of glycolide. The article focuses on the analysis and discussion of factors affecting the purity of glycolide in the synthesis, purification process selection, solvent recrystallization purification, and storage of polymer-grade glycolide, and proposes improvements to reduce the content of acid and water in glycolide during production. By analyzing the influencing factors, the article clarifies the control indicators in the production process of polymer-grade glycolide, which has guiding significance for the production process of PGA.
Glycolide / Polyglycolic acid / Biodegradable materials / Recrystallization / Water / Acid
| 1 |
2024—2029年中国乙交酯市场专题研究及标准化可行性评估报告,2024宇博智业产业研究院.
|
| 2 |
2024—2029年中国PGA市场专题研究及标准化可行性评估报告,2024宇博智业产业研究院.
|
| 3 |
2024—2029年中国可降解塑料市场专题研究及标准化可行性评估报告,2024宇博智业产业研究院.
|
| 4 |
吴双全,张佩华,郭正,等.聚乙交酯纤维的体外降解性能[J].纺织学报,2009,30(4):5-9.
|
| 5 |
姜泽钰,彭晨,王宇,等.聚乙醇酸单体乙交酯合成研究进展[J].塑料科技,2023,51(12):94-98.
|
| 6 |
孙政,崔爱军,姜海建,等.煤制乙二醇副产物乙醇酸甲酯合成乙交酯工艺研究[J].现代化工,2014,34(9):96-99.
|
| 7 |
张婧,施云海.乙交酯的合成研究进展[J].化学世界,2010,10(13):13-14.
|
| 8 |
姜海建.溶剂共沸解聚法制备乙交酯及其催化聚合反应研究[D].常州:常州大学,2015.
|
| 9 |
申雄军,阮建明.乙交酯的提纯方法:CN100999516A[P].2007-07-18.
|
| 10 |
刘伟,孙朝阳,何佳欢,等.一种减压蒸馏-熔融结晶合精制乙交酯的方法:CN107304196A[P].2017-10-31.
|
| 11 |
康小玲,丁永良,张飞,等.一种制备高纯度乙交酯的方法:CN113336739A[P].2021-09-03.
|
| 12 |
吴清云,周维友,何明阳,等.乙交酯的合成[J].精细化工,2012,29(4):413-416.
|
| 13 |
|
| 14 |
朱煜,王睿,田鹏飞,等.乙交酯精制的研究进展[J].合成纤维工业,2015,38(5):43-46.
|
| 15 |
杨飞,杨亚明,刘建红,等.聚乙交酯公斤级生产途径探索[J].北京理工大学学报,2001,21(4):518-523.
|
| 16 |
陶龙,刘洪忠,杨学超,等.乙醇酸酯低聚物的制备系统和制备方法:CN117101162A[P].2023-09-11.
|
| 17 |
温亮,尹甜,薛亚奇,等.共沸缩聚-解聚法高效合成乙交酯[J].高分子通报,2023,36(4):459-465.
|
| 18 |
董浩,马丽霞,吴倩倩,等.催化剂用量与反应时间对乙交酯-丙交酯5050共聚物微结构的影响[J].生物医学工程研究,2020,39(1):84-89.
|
| 19 |
高雪莉.乙醇酸的合成工艺研究[D].天津:河北工业大学,2014.
|
| 20 |
彭松,崔爱军,尹芳华,等.醇洗法纯化乙交酯的工艺及对开环聚合反应的影响[J].化工进展,2015,34(4):1059-1063.
|
| 21 |
王法庭,马颖足,卢利飞,等.一种可降解材料中间体提纯回收的工艺系统和方法:CN117180839A[P].2023-09-05.
|
| 22 |
汪威雨,邹俊.聚乙交酯的水解性能及热稳定的研究[D].镇江:江苏科技大学,2019.
|
| 23 |
闫国春,刘洪亮,姜兴剑,等.一种乙交酯的提纯系统及提纯方法:CN117180789A[P].2023-09-11.
|
| 24 |
边宇飞,于佩潜,孙峤昳,等.开环聚合条件对聚乙交酯热稳定性的影响[J].合成树脂及塑料,2023,40(2):11-17, 22.
|
| 25 |
刘洪忠,王法庭,姚永宁,等.一种乙交酯固液混合物的分离系统及分离方法:CN117180789A[P].2023-09-11.
|
| 26 |
刘洪忠,刘洪亮,卢利飞,等.一种固液洗涤分离装置及包含其的分离利用系统及方法:CN116999959A[P].2023-09-08.
|
| 27 |
王法庭,黄从军,马颖足,等.一种乙交酯结晶母液中溶剂的分离回收系统及方法:CN117180839A[P].2023-08-30.
|
| 28 |
王法庭,马颖足,卢利飞,等.一种粗乙交酯的提纯分离装置及提纯方法:CN117122951A[P].2023-08-30.
|
| 29 |
纪佳伟,窦岩,令永功,等.乙交酯干燥设备的结构设计与工作原理[J].化工机械,2021,48(5):756-758.
|
| 30 |
李洋.乙交酯间歇结晶过程和连续过程中多晶型选择性研究[D].天津:天津大学,2019.
|
| 31 |
姚永宁,刘洪忠,王法庭,等.一种乙交酯制备工艺中的渣相物料的回收利用方法:CN117123610A[P].2023-08-30.
|
| 32 |
陶龙,刘洪忠,党利强,等.一种气相乙交酯真空冷凝系统和气相乙交酯处理方法:CN117160067A[P].2023-09-06.
|
| 33 |
刘洪忠,马颖足,刘洪亮,等.乙交酯冷凝系统和对乙交酯气相物料进行冷凝的方法:CN117046150A[P].2023-08-30.
|
| 34 |
刘洪忠,刘洪亮,卢利飞,等.粉末输送储存系统:CN116946721A[P].2023-09-06.
|
/
| 〈 |
|
〉 |
AI Summary
