PDF(1140 KB)
Study on the Migration Properties of Ultraviolet Absorbent UV-P in Light-Resistant TPU Infusion Device
CUI Ping, CAO Qing-feng, DING Yi -mei
PDF(1140 KB)
PDF(1140 KB)
Study on the Migration Properties of Ultraviolet Absorbent UV-P in Light-Resistant TPU Infusion Device
This paper established a high performance liquid chromatography (HPLC) method for the determination of ultraviolet absorber UV-P in an light resistant thermoplastic polyurethane infusion device, and to carry out the research on the dissolution of ultraviolet absorber UV-P from disposable TPU infusion device. Six different types of injections were used to simulate the clinical application conditions, and after infusion with a light resistant TPU infusion device, they were analyzed by high-performance liquid chromatography. Kromasil C18 column was adopted, the mobile phase consisted of methanol-water (90∶10), the detection wavelength was 339 nm. The resuls show that calibration curves of UV-P are linear over the range of 0.061 4~1.638 0 mg/L (r=0.999 9), the average recoveries are both betwen 97.91% and 101.10%, the relative standard deviation is less than 2%, the signal-to-noise ratio is greater than 3, and the values of quantitation limit is 0.020 48 mg/L.The method is sensitive and good repeatability, which is suitable for the detection of UV-P dissolution in TPU infusion device.
Light-resistant thermoplastic polyurethane infusion device / Ultraviolet absorber UV-P / Dissolving out / HPLC
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