The safety of degradable plastics is the focus of research.The study was based on the determination of main components in degradable plastic bags, and the migration of acetyl-tributyl citrate (ATBC) was analyzed. The migration of ATBC from degradable plastic bags to different food simulants was detected by gas chromatography-mass spectrometry (GC-MS). The migration rule of ATBC in different temperature, thickness and food simulants was studied at 10 days. Under the same temperature and thickness of degradable plastic bags, the migration amount of ATBC in 95% ethanol simulated solution was the largest. Other conditions being equal, the smaller the thickness, the greater the amount of ATBC migration. In the same food simulation solution with the same migration time, the higher the temperature, the greater the amount of ATBC. The type of food simulation liquid, migration temperature, migration time and thickness of plastic bags have important effects on the migration of ATBC in degradable plastic bags.