In order to explore the effect of antibacterial agent on the performance of polycarbonate (PC) materials, the self-made antibacterial agent ZH001 was added to the PC by double screw extrusion granulation method, and the PC antibacterial material with high transparency antibacterial effect was obtained. The melt flow rate, the notch impact strength, tensile strength, bending properties, light transmittance, fog degree, and antibacterial properties of PC materials were tested respectively, and the performance of the PC material was compared with that of the PC materials added with commercially available antibacterial agents. The results show that the toughness of PC increases more when the amount of ZH001 is 0.6%, the notched impact strength of simply supported beam increases from 71.000 kJ/m² to 73.259 kJ/m², and the elongation at break of material increased from 75.000% to 78.425%. The antibacterial agent has little effect on the transparency and fog of PC, the light transmittancethe of PC material with 0.6% ZH001 is 90.2%, and the fog is 9.4%. The PC material with 0.6% ZH001 has excellent antimicrobial effect, with 99.99% antimicrobial rate against both Escherichia coli and Staphylococcus aureus.