Research advances in autoimmune pancreatitis with pancreatic exocrine insufficiency

Xiang AO, Chenxiao LIU, Xianda ZHANG, Taojing RAN, Chunhua ZHOU, Duowu ZOU

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Journal of Clinical Hepatol ›› 2025, Vol. 41 ›› Issue (2) : 395-400. DOI: 10.12449/JCH250230
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Research advances in autoimmune pancreatitis with pancreatic exocrine insufficiency

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Abstract

Autoimmune pancreatitis is a special type of chronic pancreatitis that can lead to abnormal pancreatic exocrine function in patients. Autoimmune pancreatitis comorbid with pancreatic exocrine insufficiency has a complex pathogenesis， and there is limited research on this topic， leading to the lack of understanding of such patients in clinical practice. This article introduces the epidemiology of autoimmune pancreatitis， briefly describes the pathogenesis of pancreatic exocrine insufficiency caused by autoimmune pancreatitis， and summarizes the various detection methods for pancreatic exocrine function， nutritional assessments， lifestyle management， and drug therapy， in order to strengthen the understanding of autoimmune pancreatitis comorbid with pancreatic exocrine insufficiency and improve the clinical diagnosis and treatment of pancreatic exocrine insufficiency.

Key words

Autoimmune Pancreatitis / Exocrine Pancreatic Insufficiency / Nutrition Therapy / Drug Therapy

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Xiang AO , Chenxiao LIU , Xianda ZHANG , et al . Research advances in autoimmune pancreatitis with pancreatic exocrine insufficiency. Journal of Clinical Hepatol. 2025, 41(2): 395-400 https://doi.org/10.12449/JCH250230

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General Project of National Natural Science Foundation of China(82270667)

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