海南省消除病毒性肝炎公共卫生危害工作实践

李维华, 熊昌富, 陈太梵, 何滨, 殷大鹏, 曾雪霞, 林锋, 陈碧玉, 曾小妹, 吴彪, 江娟, 钟璐, 张毓辉

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临床肝胆病杂志 ›› 2025, Vol. 41 ›› Issue (2) : 228-233. DOI: 10.12449/JCH250206
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海南省消除病毒性肝炎公共卫生危害工作实践

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Working practices in eliminating the public health crisis caused by viral hepatitis in Hainan Province of China

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摘要

2022年海南省政府启动了病毒性肝炎防治项目,其目标为:到2025年底18岁以上人群乙型肝炎筛查率达到90%,诊断率达到90%,治疗率达到80%;其主要干预措施为“人群预防、病例筛查、抗病毒治疗和健康管理”。截至2024年12月31日,累计筛查乙型肝炎大众人群687.5万人,筛查率为95.6%;发现HBsAg阳性者184 710例,其中确诊复核检测156 772例,诊断率为84.9%;发现慢性乙型肝炎患者50 742例,其中建立乙型肝炎专病档案进行健康管理42 921例,建档率84.6%;抗病毒治疗31 553例,治疗率62.2%。累计筛查丙型肝炎重点人群250.3万人,其中抗-HCV阳性4 870例,HCV RNA检测3 858例,诊断率为79.2%;发现HCV RNA阳性1 824例,其中接受抗病毒治疗1 194例,治疗率65.5%。对HBsAg和抗-HBs阴性、年龄在20~40岁人群免费接种乙型肝炎疫苗159 301人。通过病毒性肝炎防治项目的实施,海南省短期内发现、治疗和管理了一大批病毒性肝炎患者,明显加快了消除病毒性肝炎危害行动步伐。

Abstract

In 2022, Hainan provincial government launched the project for the prevention and control of viral hepatitis with the goals of a hepatitis B screening rate of 90%, a diagnostic rate of 90%, and a treatment rate of 80% among people aged 18 years and above by the year 2025, and the main intervention measures include population-based prevention, case screening, antiviral therapy, and health management. As of December 31, 2024, a total of 6.875 million individuals in the general population had been screened for hepatitis B, with a screening rate of 95.6%. A total of 184 710 individuals with positive HBsAg were identified, among whom 156 772 were diagnosed through serological reexamination, resulting in a diagnostic rate of 84.9%. A total of 50 742 patients with chronic hepatitis B were identified, among whom 42 921 had hepatitis B-specific health records established for health management, with a file establishment rate of 84.6%. A total of 31 553 individuals received antiviral therapy, with a treatment rate of 62.2%. A total of 2.503 million individuals at a high risk of hepatitis C were screened, among whom 4 870 tested positive for HCV antibody and 3 858 underwent HCV RNA testing, resulting in a diagnostic rate of 79.2%, and 1 824 individuals with positive HCV RNA were identified, among whom 1 194 received antiviral therapy, with a treatment rate of 65.5%. In addition, 159 301 individuals with negative HBsAg and anti-HBs and an age of 20 — 40 years were inoculated with hepatitis B vaccine free of charge. Through the implementation of the project for the prevention and control of viral hepatitis, a large number of hepatitis patients have been identified, treated, and managed in the province within a short period of time, which significantly accelerates the efforts to eliminate the crisis of viral hepatitis.

关键词

肝炎, 病毒性, 人 / 公共卫生工作 / 海南

Key words

Hepatitis, Viral, Human / Public Health Practice / Hainan

引用本文

导出引用
李维华 , 熊昌富 , 陈太梵 , . 海南省消除病毒性肝炎公共卫生危害工作实践. 临床肝胆病杂志. 2025, 41(2): 228-233 https://doi.org/10.12449/JCH250206
Weihua LI, Changfu XIONG, Taifan CHEN, et al. Working practices in eliminating the public health crisis caused by viral hepatitis in Hainan Province of China[J]. Journal of Clinical Hepatol. 2025, 41(2): 228-233 https://doi.org/10.12449/JCH250206

参考文献

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作者贡献声明

李维华负责肝炎防治项目组织管理和论文修改;熊昌富负责项目技术指导,设计论文框架并起草论文;陈太梵负责项目组织实施,协助论文撰写;何滨、殷大鹏、曾雪霞、林锋、陈碧玉、曾小妹、吴彪、江娟等负责流行病学调查方案制定、流行病学调查现场组织实施以及项目技术指导;钟璐负责数据收集、统计学分析和图表绘制;张毓辉负责项目组织领导,拟定论文写作思路,指导撰写文章并最后定稿。李维华与熊昌富对本文贡献等同,同为第一作者。

致谢

感谢中国肝炎基金会王宇理事长对海南省肝炎防治项目指导,感谢中国疾病预防控制中心赵雁林、黄飞、刘小秋、姜世闻、胡跃华、王富珍以及国家卫生健康委卫生发展研究中心苗艳青、张晓林等专家在流行病学调查抽样设计和数据统计分析等方面给予的技术支持。

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