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自体富血小板纤维蛋白应用于根尖周炎磨牙即刻种植1例报告及文献复习
贾克文,朱悦萌,陈思宇,李明慧,游佳倩,陈升,周延民
PDF(1792 KB)
PDF(1792 KB)
自体富血小板纤维蛋白应用于根尖周炎磨牙即刻种植1例报告及文献复习
)Application of autologous platelet-rich fibrin in immediate implant placement of molar with periapical periodontitis: A case report and literature review
)目的 将自体富血小板纤维蛋白（PRF）单独应用于根尖周炎磨牙即刻种植，观察其临床疗效并探讨其作用机制，以拓宽其临床应用并为其临床实践提供指导。 方法 收集1例将PRF单独应用于根尖周炎磨牙即刻种植患者的临床资料，采用锥形束CT（CBCT）和口腔扫描数据三维重建的方法对种植体周围组织改变量进行评估，并结合相关文献分析PRF的治疗方法和治疗效果。 结果 采用微创拔除患者46患牙行即刻种植的治疗方法。术前取患者自体血液30 mL（3管），将血液置于不含抗凝剂的10 mL玻璃涂层塑料管中，采用3 000 r·min－1离心10 min的方法制备3枚PRF，并将其作为唯一材料充填跳跃间隙。治疗后采用CBCT和口腔扫描三维重建对比分析，术后6个月时，种植体周围骨组织增加203.19 mm3，颊侧骨高度增加5.83 mm，且颊侧骨组织增加量大于1 mm；术后12个月时，种植体周软硬组织基本保持稳定。 结论 将自体PRF单独应用于根尖周炎磨牙即刻种植，获得了良好的治疗效果，种植体周骨组织再生且种植体周软硬组织基本保持稳定。
Objective To observe the clinical efficacy of autologous platelet-rich fibrin （PRF） application alone in immediate dental implant placement in the molars with periapical periodontitis， and to discuss the mechanism， in order to widen its clinical application and to provide the guidance for its clinical practice. Methods The clinical data of one patient who underwent immediate implant placement in the molars with periapical periodontitis using PRF as the sole material were collected. The changes in the tissues surrounding the implant were evaluated through the three-dimensional reconstruction of cone-beam CT （CBCT） and oral scan data， the therapeutic methods and outcomes of PRF treatment were analyzed combined with the relevant literatures. Results A minimally invasive extraction of the patient’s 46 diseased molar was conducted followed by the immediate implant placement. Before surgery， 30 mL of the patient’s own blood （3 tubes） was drawn， which was then placed in 10 mL glass-coated plastic tubes without anticoagulants. Three PRF were prepared with the blood by centrifuging at 3 000 r·min－1 for 10 min. These clots were used as the only filling material for the jumping gap. The postoperative CBCT and oral scan 3D reconstruction results showed that the peri-implant bone tissue was increased by 203.19 mm3， the buccal bone height was increased by 5.83 mm， and the buccal bone tissue was increased by more than 1 mm at 6 months postoperatively； after 12 months， the soft and hard tissues around the implant remained essentially stable. Conclusion The application of autologous PRF alone in immediate implant placement in the molars with periapical periodontitis achieves favorable treatment outcomes， the peri-implant bone tissue regenerates， and the peri-implant hard and soft tissues remain stable， which providing the new insights into the immediate implant treatment.
Platelet-rich fibrin / Immediate implant placement / Periapical periodontitis / Bone regeneration
R781.341
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