The new era and new situation have put forward higher requirements for talent cultivation in medical colleges. The construction of the “Situation and Policy” course in medical colleges not only faces common problems in universities， but also has its own particularity in the professional training of medical students. Therefore， based on the requirements of promoting the construction of the “Great Ideological and Political Course”， the reform of the “Situation and Policy” course in medical colleges must focus on solving the practical difficulties in concept understanding， teaching subjects， teaching content， teaching methods， and guarantee incentives， and improve the quality and level of course construction in order to achieve the goal of helping to cultivate high-quality medical talents with both morality and talent.