考察了超声辅助低共熔溶剂（Deep eutectic solvents-based ultrasound-assisted extraction，DES－UAE）提取银杏叶多酚化合物的效果，在制备的7种低共熔溶剂（Deep eutectic solvent，DES）中，氯化胆碱－乳酸因其优异的提取性能被认为是多酚提取的良好提取溶液.以多酚提取量为响应值，采用响应面法探究工艺参数对提取率的影响，而且根据提取的效果不断优化提取的工艺条件.结果表明，在40 kHz频率的超声中，使用氯化胆碱∶DL－乳酸的物质的量比为1∶3、DES中水体积分数为32.32%，提取时间50.5 min、液固比27.30 mL/g的条件下，从银杏叶提取得到13.73%的多酚物质.上述结果为银杏叶多酚化合物的提取提供了新思路，体现出了DES提取多酚化合物的优势.

In this study， the effect of deep eutectic solvents-based ultrasound-assisted extraction（DES-UAE） on the extraction of polyphenols from Ginkgo biloba leaves was investigated. Among seven prepared DES， choline chloride－DL－lactic acid was considered as a good candidate for polyphenols extraction due to its superior extraction performance. Subsequently， the response surface methodology was used to explore the effect of process parameters on the extraction rate， with the polyphenol extraction amount as the response value， and its process conditions were continuously optimized according to the extraction effect. The results showed that under the conditions of 40 kHz frequency ultrasound， the molar ratio of choline chloride： DL-lactic acid was 1∶3， the water volume fraction in DES was 32.32%， the extraction time was 50.5 min， and the liquid-solid ratio was 27.30 mL/g， 13.73% of polyphenols were extracted from ginkgo leaves. This study provides a new idea for the extraction of polyphenolic compounds from Ginkgo biloba leaves， which reflects the advantages of DES in the extraction of polyphenolic compounds.