Application of invisible orthodontic appliances in the treatment of adult skeletal malocclusions， especially in the cases requiring tooth extraction， has always been one of the challenges in invisible orthodontic technology. Our department received a 30-year-old female patient in March 2019； the patient presented with complaints of “crooked teeth and protruding mouth，” seeking orthodontic treatment to improve her facial profile. The patient had bilateral distal molar relationship， proclined maxillary and mandibular anterior teeth， and deep overjet； radiographic examination revealed an ANB angle of 6.2°， indicating a skeletal Class Ⅱ malocclusion. By extracting four first premolars and using four miniscrews， after 20 months of treatment， the extraction spaces were fully closed， the dental arch was aligned， and the occlusal relationship was favorable； the anterior teeth were retracted， the mandible showed a reverse rotation， and the soft tissue profile was significantly improved. Application of invisible orthodontic appliances in conjunction with miniscrews anchorage can achieve good three-dimensional control of tooth movement in adult extraction cases， providing a reference for clinical practitioners treating such patients.